نوع مقاله : مقاله پژوهشی

نویسندگان

1 گروه علوم خاک دانشکده کشاورزی دانشگاه ارومیه، نازلو ارومیه ایران

2 استاد گروه علوم خاک دانشکده کشاورزی دانشگاه ارومیه

3 دانشگاه ارومیه

4 دانشیار دانشکده دامپزشکی، دانشگاه ارومیه، ایران

چکیده

آنتی­بیوتیک­ها در سراسر جهان نقش مهمی در کنترل بیماری­های عفونی در انسان و حیوان ایفا می­کنند. آن­ها به دلیل ناقص بودن متابولیسم­شان در طول درمان وارد آب و خاک شده و به­ عنوان آلاینده آلی پایدار در محیط زیست محسوب می­شوند. آنتی­بیوتیک­ها براساس پایداری ذاتی در برابر تجزیه دارای محدوده وسیعی از نیمه عمر (از کمتر از یک روز تا ده سال) هستند و میزان تجزیه آنتی­بیوتیک­ها به خصوصیات فیزیکوشیمیایی آن­ها، نوع خاک و عوامل اقلیمی (دما، رطوبت و ...) بستگی دارد. بخش باقیمانده این ترکیبات می­تواند به­عنوان عوامل ضد میکروبی بر جوامع میکروبی خاک و به نوبه خود بر سلامت خاک پیامدهای منفی بگذارند. در نهایت آنتی­بیوتیک­ها از طریق جذبشان توسط محصولات زراعی، وارد زنجیره غذایی انسان شده و مقاومت آنتی­بیوتیکی در انسان ایجاد می­کنند. با این حال بسیاری از نتایج مبهم بوده که این نشان می­دهد تعیین دقیق سرنوشت آنتی­بیوتیک­ها و برآورد خطر ناشی از مقاومت آنتی­بیوتیکی یک چالش بزرگ است. در این مقاله سرنوشت آنتی­بیوتیک­ها در خاک (جذب و تجزیه)، تاثیرشان بر عملکرد جامعه میکروبی خاک، جذب توسط گیاه و تاثیر بر امنیت غذایی انسان مرور می­شود.

کلیدواژه‌ها

عنوان مقاله [English]

Antibiotic residues in the soil,; a threat to human health

نویسندگان [English]

  • Mahrokh Sharifmand 1
  • ebrahim sepehr 2
  • MirHassan Rasouli-Sadaghiani 3
  • siamak Asri-Rezaei 4

1 Iran

2 Professor of Dept. of Soil Science, Faculty of Agriculture, Urmia University, Urmia, Iran

3 Dept of Soil Sci. Urmia Uni

4 Associate Prof. Faculty of Veterinary Medicine, Urmia University, Urmia, Iran

چکیده [English]

Antibiotics play a key role in the management of infectious diseases in humans and animals all over the world. Because the majority of antibiotics are not completely metabolized in the bodies of humans and animals, a high percentage of administered drugs is discharged into water and soil, thus it is known as environmentally stable organic pollutants. Based on inherent stability to degradation, antibiotics have the large range of half-lives in soil, between <1 day and 10 years. The physiochemical properties of antibiotics, soil type and climatic factors (temperature, humidity, etc.) affect the degradation of antibiotics. The remainder of these compounds, as antimicrobial agents have negative effects on soil microbial communities and, in turn, on soil health. Finally, antibiotics can be entered to the food chain through their uptake by crops and lead to antibiotic resistance in humans. However, many ambiguous results indicate that precise assessment of the fate of antibiotics and the estimation of risk of human health due to antibiotic resistance is a great challenge. In this paper, the fate of antibiotics in soil (sorption and degradation), their impact on soil microbial community function, uptake by plants and the impact on human food security are reviewed.

کلیدواژه‌ها [English]

  • Fate of antibiotics
  • Microbial community function
  • Antibiotic resistance
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